NHS and HSC PICs should be established through a subcontracting agreement with the participating NHS and HSC organisation that the ICP supports. Appropriate arrangements for data processing should be made using the corresponding model agreement: templates, guidelines and feedback information are available in the “Templates and supporting documents” section on the IRAS help pages. Nationally approved standard location agreements help speed up the contracting process of industry-sponsored studies carried out in the NHS by creating the need for site-by-site verifications and local legal agreements. This enables an earlier start-up, improves the speed of industry-sponsored clinical trials and allows NHS patients to access innovative treatments faster. The series of model location agreements is supported by guidelines that set out the objectives and will detail how the agreement should be used in the development of clinical research contracts sponsored by pharmaceutical, biopharmaceutical or medical companies. Revised in February 2018, the Clinical Trial Agreement (mCTA) and Clinical Research Organisation model Clinical Trial Agreement (CRO-mCTA) models are designed to be used without modification for industry-sponsored studies of NHS/HSC patients in hospitals across the UK Health Service. The Model Clinical Trials Agreement (MCTA) of February 2018 and the Clinical Research Organisation Model Clinical Trials Agreement (CRO-mCTA) replace the national versions and are an important step in streamlining sponsored business studies across the UK healthcare system, eliminating unnecessary management. Currently, companies must spend time preparing contracts in each of the four nations for the same study, but the revised models will allow for the use of a single contract for business research and development in England, Scotland, Wales and Northern Ireland. Launched in February 2011, the Model Industry Collaborative Research Agreement (MICRA) aims to support clinical research cooperation involving the pharmaceutical and biotechnology industries, universities and NHS organisations across the UK. “This collaborative approach is an important step forward and supports our ongoing commitment to creating an effective, supportive and supportive environment for industry-sponsored studies.” The Health Research Authority (HRA) in England and health services in decentralised administrations expect sponsors (and CROs) to use the February 2018 MCTAs without modification and in line with guidelines when contracting with NHS/HSC organisations to carry out industry-sponsored studies. . . .